New study/early-phase trial for High-Risk MDS and Acute Myeloid Leukaemia (AML)

To be conducted by Dr Mili Shah and Dr Victoria Potter of King's College Hospital, London, and Professor Robert Wynn of Royal Manchester Children’s Hospital.


 

This upcoming study will focus on the use of expanded cord blood stem cells, alongside granulocytes (a type of white blood cell) in both adults and children with high-risk blood cancers, in particular very high-risk Myelodysplastic Syndromes and Acute Myeloid Leukaemia.  These cancers are incredibly difficult to cure, and even with a stem cell transplant long-term survival rates can be low, therefore this is a priority area for researchers.

The aim of this particular study is to increase the successful outcome of stem cell transplants in high risk patients.  Early studies using expanded cord blood suggest it may improve outcomes, and with the addition of granulocytes (which have shown encouraging results so far in an ongoing clinical trial with children with very high-risk disease) it is possible that a combination of the two methods will provide the best chance of preventing the disease from recurring post-transplant.

Introductory online meeting about the study June 27th 6pm


If you'd like to learn more about this study the clinicians are hosting an introductory online meeting on Thursday 27th June at 6pm.  Please email milinaresh.shah@nhs.net or robert.wynn@nhs.uk and they will send you a short questionnaire to complete.

 

 

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